The objective of the milling process is to control ingredient particles size using mills, screens and sieving technologies

“Fines” are particles

Particle size control by milling effects the tablet making process

Controlled particle size uniformity improves performance which helps to overcome many common tablet defects.

Controlled particle size helps all, except for one of the following

It is important to have a even particle size distribution but density control is not important

There are many machine types to control particle size, machine selection depends on:

A low shear includes all of the following except

All mills can be used for wet or dry powders

To many fines within the granulation